Every product in the GLY KO LINE offers maximum efficacy with minimum irritation in the treatment of the different skin diseases, offering the patient a more reliable and clinically proven solution.

The higher the pH, the more the possibility of irritation decreases.

Damage caused by U.V. rays appear to be repaired more rapidly when the GLY KO LINE formula is applied daily, 24 hours after exposure to the sun (3-4).

All the products of the GLY KO LINE have a concentration between 15 and 20% of the glycolic compound. The choice of a pH of 3.8 for each product assures patients an effective treatment for a healthier skin with a minimum of irritation (1).

The GLY KO LINE is a complete system. There are a variety of combinations to respond to any kind of skin disease.

The ability of Alpha Hydroxy Acids to reduce hyperkeratosis, to increase hydration and to act as liberating agents represents an important advance in skincare. Most of the major studies concentrate on the most effective of all the AHAs, glycolic acid. It plays a vital role by helping to normalise skin disorders. Compound products of glycolic acid can favourably influence the treatment of a number of skin diseases such as cutaneous ageing, hyperpigmentation, dry skin, greasy skin, acne, lesions due to U.V. rays, etc.

The formula chosen is accepted as the most effective. This formula is based on the following principle: the potential irritation of AHAs is much more dependent on pH than on concentration. Since normal skin pH varies from 4.2 to 5.6, the formulas containing free acids (1-2) in which pH is low can be extremely irritating for the skin, even in low concentration. These free acids can even damage the epidermis, due to their corrosive nature.

The higher the pH, the lesser the risk of significant irritation.

Instead of limiting the concentrations of glycolic acid in the formulas of free acids, we have buffered the acid, which allows higher concentrations of acid, and results in an increase in efficacy without irritation (1-2).

Several journals have demonstrated that this formula can help repair damage caused by U.V. rays on the skin and that the process of exfoliation does not appear to compromise or to increase the risk of damage to skin by U.V. rays (3-4).

1. DiNardo JC, Grove GL, Moy LS. 12 % ammonium lactate vs 8 % glycolic acid. J Geriatric Derm. 1995;3:144-147.
2. DiNardo JC, Grove GL, Moy LS. Clinical and histological effects of glycolic acid at different concentrations and pH levels. J Derm Surg and Onc. Accepted for publication, May 1995.
3. Elson M. The utilization of glycolic acid in photoaging. Cos Derm. 1992; 5:12-15.
4. Ridge JM, Siegle RJ, Zuckerman J. Use of alpha hydroxy acids in the therapy for photoaged skin. J Amer Acad Derm. 1990. 23:932.
5. DiNardo JC. A comparison of salicylic acid, salicylic acid with glycolic acid and benzoyl peroxide in the treatment of acne. Cos Derm. August 1995.
6. Murad H, et al. Study shows that acne improves with glycolic acid regimen. Cos Derm. 1992:32-35.
7. Rubin MG, Becker F, Speelman P. Comparative safety and efficacy of glycolic acid peels with various pH levels.